Pharmaceutical Hot
Melt Extrusion Equipment Market Size, Market Share, Application Analysis,
Regional Outlook, Growth Trends, Key Players, Competitive Strategies And
Forecasts, 2017 To 2025
Pharmaceutical Hot
Melt Extrusion Equipment Market - Growth, Future Prospects and Competitive
Analysis, 2017-2025, the global pharmaceutical hot melt extrusion equipment
market was valued at US$ 26.1 Mn in 2016, and is expected to reach US$ 39 Mn by
2025, expanding at a CAGR of 4.5% from 2017 to 2025.
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Market Insights
The use of hot melt
extrusion technology in pharmaceutical application is steadily increasing due
to its ability of manufacture novel drugs with improved bioavailability.
Development of novel drugs with challenged solubility and bioavailability has
urged the adoption of HME process in drug-delivery systems, particularly in
solid dosage forms and transdermal patches. Hot melt extrusion involves the
application of heat, agitation and pressure through extrusion channel for
mixing materials and forcing them into desired form. Growth in number of novel
drugs with challenged bioavailability and the urgency for introducing such
drugs in the market are the key drivers contributing to the growth in demand
for hot melt extrusion in pharmaceutical application.
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Among the considered
extruder types, twin-screw extruders (TSE) are the most widely used process for
development of solid dosage forms and it uses both distributive and dispersive
mixing. Driven by the FDA’s process analytical technology initiative (PAT), the
use of TSE in pharmaceutical manufacturing has been adopted by every major
pharmaceutical manufacturer. The process analytical technology initiative has
encouraged formulation of new dosages with TSE technology. Further efforts are
also being taken for designing TSE systems for testing early-stage materials
that are available only in minimal quantities.
Geographically,
North America is the largest regional market for pharmaceutical hot melt
extrusion equipment with a market share of over 35% in 2016. Existence of a
multitude of pharmaceutical manufacturers that have adopted HME systems in drug
manufacturing and widespread installation of HME in cGMP practices will ensure
the dominance of North America market on the global front. The demand for HME
systems in Europe pharmaceutical industry is also expected to remain steady
during the forecast period. High demand for novel drug manufacturing
technologies mainly drive the Europe market. However, growing CMO and research
activities will facilitate the faster growth of Asia Pacific market.
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Presence of a
several manufacturers has made the competition in the global pharmaceutical hot
melt extrusion equipment fragmented, with a handful of companies enjoying global
prominence. Some of the major players in the global pharmaceutical hot melt
extrusion equipment market are Baker Perkins Ltd., Coperion GmbH, Gabler GmbH
& Co. KG, Milacron Holdings Corp., Leistritz Advanced Technologies Corp.,
Thermo Fisher Scientific, Inc. and Xtrutech Ltd.
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